ANO2

anoctamin 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
27323328 Saos-2,H1299, HT18, MCF7, MDA-MB-231, Li-Fraumeni Human YES
29548335 Saos-2 Human YES

GO terms:

Biological Process:
ion transmembrane transport [GO:0034220],
chloride transmembrane transport [GO:1902476],
ion transport [GO:0006811],
chloride transport [GO:0006821],

Molecular Function:
intracellular calcium activated chloride channel activity [GO:0005229],
protein binding [GO:0005515],
protein homodimerization activity [GO:0042803],
protein heterodimerization activity [GO:0046982],
chloride channel activity [GO:0005254],
phospholipid scramblase activity [GO:0017128],
protein dimerization activity [GO:0046983],

Cellular Component:
nucleoplasm [GO:0005654],
plasma membrane [GO:0005886],
chloride channel complex [GO:0034707],
non-motile cilium [GO:0097730],
membrane [GO:0016020],
integral component of membrane [GO:0016021],