ABCC2

ATP binding cassette subfamily C member 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Li Fraumeni Human YES

GO terms:

Biological Process:
bilirubin transport [GO:0015723],
transmembrane transport [GO:0055085],
drug transmembrane transport [GO:0006855],
mercury ion transport [GO:0015694],
canalicular bile acid transport [GO:0015722],
prostaglandin transport [GO:0015732],
antibiotic metabolic process [GO:0016999],
cellular chloride ion homeostasis [GO:0030644],
response to drug [GO:0042493],
response to estrogen [GO:0043627],
thyroid hormone transport [GO:0070327],
benzylpenicillin metabolic process [GO:1901086],

Molecular Function:
protein binding [GO:0005515],
ATP binding [GO:0005524],
organic anion transmembrane transporter activity [GO:0008514],
bilirubin transmembrane transporter activity [GO:0015127],
ATPase activity, coupled to transmembrane movement of substances [GO:0042626],
protein domain specific binding [GO:0019904],

Cellular Component:
plasma membrane [GO:0005886],
integral component of plasma membrane [GO:0005887],
cell surface [GO:0009986],
membrane [GO:0016020],
apical plasma membrane [GO:0016324],
brush border membrane [GO:0031526],
intercellular canaliculus [GO:0046581],