AMPD3

adenosine monophosphate deaminase 3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES
29548335 Saos-2, Li-Fraumeni Human YES

GO terms:

Biological Process:
IMP biosynthetic process [GO:0006188],
AMP catabolic process [GO:0006196],
IMP salvage [GO:0032264],
erythrocyte homeostasis [GO:0034101],
purine-containing compound salvage [GO:0043101],
neutrophil degranulation [GO:0043312],
ADP metabolic process [GO:0046031],
AMP metabolic process [GO:0046033],
ATP metabolic process [GO:0046034],
GTP metabolic process [GO:0046039],
energy homeostasis [GO:0097009],
nucleotide metabolic process [GO:0009117],
purine ribonucleoside monophosphate biosynthetic process [GO:0009168],

Molecular Function:
AMP deaminase activity [GO:0003876],
protein binding [GO:0005515],
metal ion binding [GO:0046872],
hydrolase activity [GO:0016787],
deaminase activity [GO:0019239],

Cellular Component:
extracellular region [GO:0005576],
cytosol [GO:0005829],
secretory granule lumen [GO:0034774],
ficolin-1-rich granule lumen [GO:1904813],