AMPD2

adenosine monophosphate deaminase 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2, Li-Fraumeni Human YES

GO terms:

Biological Process:
IMP biosynthetic process [GO:0006188],
IMP salvage [GO:0032264],
purine-containing compound salvage [GO:0043101],
AMP metabolic process [GO:0046033],
cyclic purine nucleotide metabolic process [GO:0052652],
energy homeostasis [GO:0097009],
nucleotide metabolic process [GO:0009117],
purine ribonucleoside monophosphate biosynthetic process [GO:0009168],
cholesterol homeostasis [GO:0042632],
ATP metabolic process [GO:0046034],
GTP metabolic process [GO:0046039],
glomerular visceral epithelial cell development [GO:0072015],

Molecular Function:
AMP deaminase activity [GO:0003876],
protein binding [GO:0005515],
metal ion binding [GO:0046872],
hydrolase activity [GO:0016787],
deaminase activity [GO:0019239],

Cellular Component:
cytosol [GO:0005829],