AMOT

angiomotin

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
30987592 MCF7 Breast Human YES

GO terms:

Biological Process:
angiogenesis [GO:0001525],
vasculogenesis [GO:0001570],
in utero embryonic development [GO:0001701],
gastrulation with mouth forming second [GO:0001702],
establishment of cell polarity involved in ameboidal cell migration [GO:0003365],
chemotaxis [GO:0006935],
negative regulation of angiogenesis [GO:0016525],
actin cytoskeleton organization [GO:0030036],
regulation of cell migration [GO:0030334],
negative regulation of GTPase activity [GO:0034260],
cellular protein localization [GO:0034613],
hippo signaling [GO:0035329],
positive regulation of embryonic development [GO:0040019],
cell migration involved in gastrulation [GO:0042074],
negative regulation of vascular permeability [GO:0043116],
blood vessel endothelial cell migration [GO:0043534],
positive regulation of blood vessel endothelial cell migration [GO:0043536],
blood vessel morphogenesis [GO:0048514],
regulation of small GTPase mediated signal transduction [GO:0051056],

Molecular Function:
protein binding [GO:0005515],
signaling receptor activity [GO:0038023],
angiostatin binding [GO:0043532],

Cellular Component:
stress fiber [GO:0001725],
ruffle [GO:0001726],
nucleus [GO:0005634],
cytoplasm [GO:0005737],
actin filament [GO:0005884],
bicellular tight junction [GO:0005923],
COP9 signalosome [GO:0008180],
external side of plasma membrane [GO:0009897],
cell surface [GO:0009986],
integral component of membrane [GO:0016021],
lamellipodium [GO:0030027],
cell junction [GO:0030054],
endocytic vesicle [GO:0030139],
cytoplasmic vesicle [GO:0031410],
cytosol [GO:0005829],