AKR1B10

aldo-keto reductase family 1 member B10

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES
30626320 HBEC Human NO

GO terms:

Biological Process:
retinoid metabolic process [GO:0001523],
farnesol catabolic process [GO:0016488],
retinol metabolic process [GO:0042572],
daunorubicin metabolic process [GO:0044597],
doxorubicin metabolic process [GO:0044598],
oxidation-reduction process [GO:0055114],

Molecular Function:
retinal dehydrogenase activity [GO:0001758],
alditol:NADP+ 1-oxidoreductase activity [GO:0004032],
aldo-keto reductase (NADP) activity [GO:0004033],
protein binding [GO:0005515],
alcohol dehydrogenase (NADP+) activity [GO:0008106],
oxidoreductase activity [GO:0016491],
geranylgeranyl reductase activity [GO:0045550],
allyl-alcohol dehydrogenase activity [GO:0047655],
indanol dehydrogenase activity [GO:0047718],
NADP-retinol dehydrogenase activity [GO:0052650],
retinal binding [GO:0016918],
NADP+ binding [GO:0070401],
NADPH binding [GO:0070402],

Cellular Component:
extracellular region [GO:0005576],
mitochondrion [GO:0005739],
lysosome [GO:0005764],
cytosol [GO:0005829],