AKAP12

A-kinase anchoring protein 12

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
30323895 HeLa Lung Mouse NO

GO terms:

Biological Process:
protein targeting [GO:0006605],
G-protein coupled receptor signaling pathway [GO:0007186],
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193],
regulation of protein kinase A signaling [GO:0010738],
positive regulation of protein kinase A signaling [GO:0010739],
modulation of synaptic transmission [GO:0050804],
regulation of protein kinase C signaling [GO:0090036],
signal transduction [GO:0007165],

Molecular Function:
protein binding [GO:0005515],
adenylate cyclase binding [GO:0008179],
protein kinase A binding [GO:0051018],
receptor signaling complex scaffold activity [GO:0030159],

Cellular Component:
cytoplasm [GO:0005737],
cytosol [GO:0005829],
cytoskeleton [GO:0005856],
plasma membrane [GO:0005886],
focal adhesion [GO:0005925],
cell cortex [GO:0005938],
membrane [GO:0016020],