apoptosis inducing factor mitochondria associated 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
apoptotic mitochondrial changes [GO:0008637],
positive regulation of apoptotic process [GO:0043065],
oxidation-reduction process [GO:0055114],
respiratory electron transport chain [GO:0022904],
regulation of apoptotic process [GO:0042981],

Molecular Function:
DNA binding [GO:0003677],
electron-transferring-flavoprotein dehydrogenase activity [GO:0004174],
oxidoreductase activity [GO:0016491],
flavin adenine dinucleotide binding [GO:0050660],

Cellular Component:
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],
mitochondrial outer membrane [GO:0005741],
lipid particle [GO:0005811],
cytosol [GO:0005829],
membrane [GO:0016020],
integral component of membrane [GO:0016021],
extracellular space [GO:0005615],