ATP binding cassette subfamily A member 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2, Li-Fraumeni Human YES

GO terms:

Biological Process:
regulation of transcription from RNA polymerase II promoter [GO:0006357],
lipid metabolic process [GO:0006629],
lipid transport [GO:0006869],
regulation of intracellular cholesterol transport [GO:0032383],
response to drug [GO:0042493],
cholesterol homeostasis [GO:0042632],
response to steroid hormone [GO:0048545],
transmembrane transport [GO:0055085],
response to cholesterol [GO:0070723],
cholesterol metabolic process [GO:0008203],

Molecular Function:
nucleotide binding [GO:0000166],
lipid transporter activity [GO:0005319],
ATP binding [GO:0005524],
ATPase activity [GO:0016887],
ATPase activity, coupled to transmembrane movement of substances [GO:0042626],

Cellular Component:
lysosome [GO:0005764],
lysosomal membrane [GO:0005765],
endosome [GO:0005768],
microtubule organizing center [GO:0005815],
endosome membrane [GO:0010008],
membrane [GO:0016020],
integral component of membrane [GO:0016021],
cytoplasmic vesicle [GO:0031410],
ATP-binding cassette (ABC) transporter complex [GO:0043190],
intracellular membrane-bounded organelle [GO:0043231],