adenylosuccinate synthase like 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Saos-2 Human YES

GO terms:

Biological Process:
purine nucleotide metabolic process [GO:0006163],
purine nucleotide biosynthetic process [GO:0006164],
AMP biosynthetic process [GO:0006167],
aspartate metabolic process [GO:0006531],
purine ribonucleoside monophosphate biosynthetic process [GO:0009168],
'de novo' AMP biosynthetic process [GO:0044208],
IMP metabolic process [GO:0046040],
immune system process [GO:0002376],
glutamine metabolic process [GO:0006541],
response to muscle activity [GO:0014850],
cellular response to drug [GO:0035690],
response to starvation [GO:0042594],
cellular response to electrical stimulus [GO:0071257],

Molecular Function:
nucleotide binding [GO:0000166],
GTPase activity [GO:0003924],
adenylosuccinate synthase activity [GO:0004019],
protein binding [GO:0005515],
GTP binding [GO:0005525],
ligase activity [GO:0016874],
protein homodimerization activity [GO:0042803],
metal ion binding [GO:0046872],
actin filament binding [GO:0051015],
magnesium ion binding [GO:0000287],
phosphate ion binding [GO:0042301],

Cellular Component:
cytoplasm [GO:0005737],
membrane [GO:0016020],
cytosol [GO:0005829],