ADH5

alcohol dehydrogenase 5 (class III), chi polypeptide

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES
29581312 HEK293, PCNs, MEF Human, mouse NO

GO terms:

Biological Process:
retinoid metabolic process [GO:0001523],
respiratory system process [GO:0003016],
ethanol oxidation [GO:0006069],
peptidyl-cysteine S-nitrosylation [GO:0018119],
electron transport chain [GO:0022900],
response to lipopolysaccharide [GO:0032496],
positive regulation of blood pressure [GO:0045777],
formaldehyde catabolic process [GO:0046294],
response to nitrosative stress [GO:0051409],
response to redox state [GO:0051775],
ethanol catabolic process [GO:0006068],
oxidation-reduction process [GO:0055114],

Molecular Function:
alcohol dehydrogenase activity, zinc-dependent [GO:0004024],
fatty acid binding [GO:0005504],
zinc ion binding [GO:0008270],
electron carrier activity [GO:0009055],
formaldehyde dehydrogenase activity [GO:0018467],
protein homodimerization activity [GO:0042803],
S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903],
alcohol dehydrogenase (NAD) activity [GO:0004022],
oxidoreductase activity [GO:0016491],
metal ion binding [GO:0046872],

Cellular Component:
mitochondrion [GO:0005739],
cytosol [GO:0005829],
extracellular exosome [GO:0070062],
nucleus [GO:0005634],
cytoplasm [GO:0005737],