ADGRV1

adhesion G protein-coupled receptor V1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA286 Skin, Lung Human YES

GO terms:

Biological Process:
cell surface receptor signaling pathway [GO:0007166],
G-protein coupled receptor signaling pathway [GO:0007186],
negative regulation of adenylate cyclase activity [GO:0007194],
nervous system development [GO:0007399],
visual perception [GO:0007601],
sensory perception of sound [GO:0007605],
positive regulation of protein kinase A signaling [GO:0010739],
positive regulation of bone mineralization [GO:0030501],
regulation of protein stability [GO:0031647],
establishment of protein localization [GO:0045184],
photoreceptor cell maintenance [GO:0045494],
maintenance of animal organ identity [GO:0048496],
inner ear development [GO:0048839],
neurological system process [GO:0050877],
detection of mechanical stimulus involved in sensory perception of sound [GO:0050910],
sensory perception of light stimulus [GO:0050953],
inner ear receptor stereocilium organization [GO:0060122],
cellular response to calcium ion [GO:0071277],
positive regulation of protein kinase C signaling [GO:0090037],
self proteolysis [GO:0097264],
cell-cell adhesion [GO:0098609],
cell communication [GO:0007154],
signal transduction [GO:0007165],
multicellular organism development [GO:0007275],
response to stimulus [GO:0050896],

Molecular Function:
G-protein alpha-subunit binding [GO:0001965],
G-protein coupled receptor activity [GO:0004930],
calcium ion binding [GO:0005509],
protein binding [GO:0005515],
adenylate cyclase inhibitor activity [GO:0010855],
hydrolase activity [GO:0016787],
transmembrane signaling receptor activity [GO:0004888],
myosin binding [GO:0017022],

Cellular Component:
photoreceptor inner segment [GO:0001917],
stereocilia ankle link [GO:0002141],
stereocilia ankle link complex [GO:0002142],
cytoplasm [GO:0005737],
plasma membrane [GO:0005886],
cell surface [GO:0009986],
membrane [GO:0016020],
integral component of membrane [GO:0016021],
receptor complex [GO:0043235],
synapse [GO:0045202],
stereocilium membrane [GO:0060171],
extracellular exosome [GO:0070062],
periciliary membrane compartment [GO:1990075],
USH2 complex [GO:1990696],
extracellular region [GO:0005576],
photoreceptor connecting cilium [GO:0032391],
stereocilium [GO:0032420],
cell projection [GO:0042995],
perinuclear region of cytoplasm [GO:0048471],