ADGRG1

adhesion G protein-coupled receptor G1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Li Fraumeni Human YES
30987592 MCF7 Breast Human YES

GO terms:

Biological Process:
angiogenesis [GO:0001525],
cell adhesion [GO:0007155],
cell surface receptor signaling pathway [GO:0007166],
G-protein coupled receptor signaling pathway [GO:0007186],
adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189],
Rho protein signal transduction [GO:0007266],
cell-cell signaling [GO:0007267],
brain development [GO:0007420],
negative regulation of cell proliferation [GO:0008285],
vascular endothelial growth factor production [GO:0010573],
cell migration [GO:0016477],
cerebral cortex regionalization [GO:0021796],
cerebral cortex radial glia guided migration [GO:0021801],
layer formation in cerebral cortex [GO:0021819],
positive regulation of Rho protein signal transduction [GO:0035025],
positive regulation of cell adhesion [GO:0045785],
protein kinase C signaling [GO:0070528],
seminiferous tubule development [GO:0072520],
positive regulation of neural precursor cell proliferation [GO:2000179],
negative regulation of neuron migration [GO:2001223],
signal transduction [GO:0007165],
multicellular organism development [GO:0007275],
nervous system development [GO:0007399],
cell differentiation [GO:0030154],

Molecular Function:
G-protein coupled receptor activity [GO:0004930],
collagen binding [GO:0005518],
heparin binding [GO:0008201],
extracellular matrix binding [GO:0050840],
transmembrane signaling receptor activity [GO:0004888],

Cellular Component:
integral component of plasma membrane [GO:0005887],
integral component of membrane [GO:0016021],
membrane raft [GO:0045121],
extracellular exosome [GO:0070062],
glial limiting end-foot [GO:0097451],
extracellular region [GO:0005576],
plasma membrane [GO:0005886],
membrane [GO:0016020],