ADGRE5

adhesion G protein-coupled receptor E5

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES

GO terms:

Biological Process:
inflammatory response [GO:0006954],
immune response [GO:0006955],
cell adhesion [GO:0007155],
cell surface receptor signaling pathway [GO:0007166],
G-protein coupled receptor signaling pathway [GO:0007186],
adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189],
cell-cell signaling [GO:0007267],
neutrophil degranulation [GO:0043312],
signal transduction [GO:0007165],
positive regulation of synapse assembly [GO:0051965],

Molecular Function:
transmembrane signaling receptor activity [GO:0004888],
G-protein coupled receptor activity [GO:0004930],
calcium ion binding [GO:0005509],
protein binding [GO:0005515],

Cellular Component:
plasma membrane [GO:0005886],
integral component of plasma membrane [GO:0005887],
focal adhesion [GO:0005925],
membrane [GO:0016020],
secretory granule membrane [GO:0030667],
extracellular exosome [GO:0070062],
integral component of membrane [GO:0016021],