ArfGAP with dual PH domains 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
30987592 MCF7 Breast Human YES

GO terms:

Biological Process:
heart development [GO:0007507],
positive regulation of GTPase activity [GO:0043547],
inositol lipid-mediated signaling [GO:0048017],

Molecular Function:
GTPase activator activity [GO:0005096],
protein binding [GO:0005515],
phosphatidylinositol-4,5-bisphosphate binding [GO:0005546],
phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547],
protein binding, bridging [GO:0030674],
phosphatidylinositol-3,4-bisphosphate binding [GO:0043325],
inositol 1,3,4,5 tetrakisphosphate binding [GO:0043533],
metal ion binding [GO:0046872],
1-phosphatidylinositol binding [GO:0005545],
phosphatidylinositol bisphosphate binding [GO:1902936],

Cellular Component:
cytoplasm [GO:0005737],
mitochondrial envelope [GO:0005740],
plasma membrane [GO:0005886],
membrane [GO:0016020],