CARS

cysteinyl-tRNA synthetase

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
tRNA aminoacylation for protein translation [GO:0006418],
cysteinyl-tRNA aminoacylation [GO:0006423],
translation [GO:0006412],

Molecular Function:
tRNA binding [GO:0000049],
cysteine-tRNA ligase activity [GO:0004817],
protein binding [GO:0005515],
ATP binding [GO:0005524],
protein homodimerization activity [GO:0042803],
metal ion binding [GO:0046872],
nucleotide binding [GO:0000166],
aminoacyl-tRNA ligase activity [GO:0004812],
ligase activity [GO:0016874],

Cellular Component:
cytoplasm [GO:0005737],
cytosol [GO:0005829],