CARM1

coactivator associated arginine methyltransferase 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
23837869 HeLa, HDF Human NO

GO terms:

Biological Process:
regulation of growth plate cartilage chondrocyte proliferation [GO:0003420],
regulation of transcription, DNA-templated [GO:0006355],
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977],
aging [GO:0007568],
positive regulation of cell proliferation [GO:0008284],
viral process [GO:0016032],
histone methylation [GO:0016571],
regulation of lipid metabolic process [GO:0019216],
peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919],
intracellular estrogen receptor signaling pathway [GO:0030520],
negative regulation of protein binding [GO:0032091],
regulation of intracellular estrogen receptor signaling pathway [GO:0033146],
histone arginine methylation [GO:0034969],
histone H3-R2 methylation [GO:0034970],
histone H3-R17 methylation [GO:0034971],
positive regulation of fat cell differentiation [GO:0045600],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
positive regulation of NF-kappaB transcription factor activity [GO:0051092],
response to cAMP [GO:0051591],
endochondral bone morphogenesis [GO:0060350],
protein localization to chromatin [GO:0071168],
regulation of mRNA binding [GO:1902415],
negative regulation of dendrite development [GO:2000171],
chromatin organization [GO:0006325],
protein methylation [GO:0006479],
intracellular steroid hormone receptor signaling pathway [GO:0030518],
methylation [GO:0032259],

Molecular Function:
transcription coactivator activity [GO:0003713],
protein binding [GO:0005515],
beta-catenin binding [GO:0008013],
protein methyltransferase activity [GO:0008276],
histone-arginine N-methyltransferase activity [GO:0008469],
protein-arginine N-methyltransferase activity [GO:0016274],
ligand-dependent nuclear receptor transcription coactivator activity [GO:0030374],
protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242],
histone methyltransferase activity (H3-R17 specific) [GO:0035642],
histone methyltransferase activity [GO:0042054],
protein homodimerization activity [GO:0042803],
transcription regulatory region DNA binding [GO:0044212],
lysine-acetylated histone binding [GO:0070577],
methyltransferase activity [GO:0008168],
transferase activity [GO:0016740],

Cellular Component:
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
cytosol [GO:0005829],
RNA polymerase II transcription factor complex [GO:0090575],
macromolecular complex [GO:0032991],