calpain 5

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Li Fraumeni Human YES

GO terms:

Biological Process:
proteolysis [GO:0006508],
signal transduction [GO:0007165],

Molecular Function:
calcium-dependent cysteine-type endopeptidase activity [GO:0004198],
peptidase activity [GO:0008233],
cysteine-type peptidase activity [GO:0008234],
hydrolase activity [GO:0016787],

Cellular Component:
cytoplasm [GO:0005737],
focal adhesion [GO:0005925],
cell surface [GO:0009986],
extracellular exosome [GO:0070062],
synapse [GO:0045202],