capping actin protein, gelsolin like

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Li Fraumeni Human YES

GO terms:

Biological Process:
extracellular matrix disassembly [GO:0022617],
barbed-end actin filament capping [GO:0051016],
macromolecular complex assembly [GO:0065003],
positive regulation of podosome assembly [GO:0071803],
cell projection assembly [GO:0030031],
actin filament capping [GO:0051693],
cellular response to interferon-gamma [GO:0071346],

Molecular Function:
protein binding [GO:0005515],
protein domain specific binding [GO:0019904],
macromolecular complex binding [GO:0044877],
cadherin binding [GO:0045296],
actin filament binding [GO:0051015],
actin binding [GO:0003779],

Cellular Component:
ruffle [GO:0001726],
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
nucleolus [GO:0005730],
cytoplasm [GO:0005737],
centriole [GO:0005814],
F-actin capping protein complex [GO:0008290],
lamellipodium [GO:0030027],
melanosome [GO:0042470],
extracellular exosome [GO:0070062],
mitotic spindle [GO:0072686],
Flemming body [GO:0090543],
extracellular space [GO:0005615],
cell projection [GO:0042995],
phagocytic vesicle [GO:0045335],