CAMK2N1

calcium/calmodulin dependent protein kinase II inhibitor 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Li Fraumeni Human YES

GO terms:

Biological Process:
negative regulation of protein kinase activity [GO:0006469],
negative regulation of cell proliferation [GO:0008285],
positive regulation of gene expression [GO:0010628],
negative regulation of cell cycle [GO:0045786],
negative regulation of proteolysis [GO:0045861],
negative regulation of ERK1 and ERK2 cascade [GO:0070373],
negative regulation of cyclin-dependent protein kinase activity [GO:1904030],

Molecular Function:
calcium-dependent protein kinase inhibitor activity [GO:0008427],
protein kinase binding [GO:0019901],
protein kinase inhibitor activity [GO:0004860],

Cellular Component:
cellular_component [GO:0005575],
postsynaptic density [GO:0014069],
cell junction [GO:0030054],
dendrite [GO:0030425],
neuronal cell body [GO:0043025],
postsynaptic membrane [GO:0045211],
plasma membrane [GO:0005886],
membrane [GO:0016020],
neuron projection [GO:0043005],
synapse [GO:0045202],