CAMK2B

calcium/calmodulin dependent protein kinase II beta

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Saos-2, Li-Fraumeni Human YES
30987592 MCF7 Breast Human YES

GO terms:

Biological Process:
protein phosphorylation [GO:0006468],
signal transduction [GO:0007165],
positive regulation of neuron projection development [GO:0010976],
regulation of skeletal muscle adaptation [GO:0014733],
protein autophosphorylation [GO:0046777],
regulation of long-term neuronal synaptic plasticity [GO:0048169],
regulation of synapse structural plasticity [GO:0051823],
regulation of calcium ion transport [GO:0051924],
interferon-gamma-mediated signaling pathway [GO:0060333],
regulation of dendritic spine development [GO:0060998],
positive regulation of dendritic spine morphogenesis [GO:0061003],
positive regulation of synapse maturation [GO:0090129],
regulation of cellular response to heat [GO:1900034],
regulation of neuron migration [GO:2001222],
G1/S transition of mitotic cell cycle [GO:0000082],
inhibitory G-protein coupled receptor phosphorylation [GO:0002030],
calcium ion transport [GO:0006816],
nervous system development [GO:0007399],
phosphorylation [GO:0016310],
peptidyl-serine phosphorylation [GO:0018105],
cell differentiation [GO:0030154],
regulation of synaptic transmission, cholinergic [GO:0032222],
positive regulation of phospholipase A2 activity [GO:0032430],
response to cadmium ion [GO:0046686],
cell projection morphogenesis [GO:0048858],
neuromuscular process controlling balance [GO:0050885],
long-term synaptic potentiation [GO:0060291],
activation of meiosis involved in egg activation [GO:0060466],
regulation of protein localization to plasma membrane [GO:1903076],
positive regulation of apoptotic signaling pathway [GO:2001235],

Molecular Function:
actin binding [GO:0003779],
calmodulin-dependent protein kinase activity [GO:0004683],
protein binding [GO:0005515],
calmodulin binding [GO:0005516],
ATP binding [GO:0005524],
identical protein binding [GO:0042802],
protein homodimerization activity [GO:0042803],
nucleotide binding [GO:0000166],
protein kinase activity [GO:0004672],
protein serine/threonine kinase activity [GO:0004674],
kinase activity [GO:0016301],
transferase activity [GO:0016740],
protein kinase binding [GO:0019901],
phospholipase binding [GO:0043274],
structural constituent of postsynaptic actin cytoskeleton [GO:0098973],

Cellular Component:
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
microtubule organizing center [GO:0005815],
cytosol [GO:0005829],
cell junction [GO:0030054],
endocytic vesicle membrane [GO:0030666],
sarcoplasmic reticulum membrane [GO:0033017],
neuron projection [GO:0043005],
synapse [GO:0045202],
cytoskeleton [GO:0005856],
postsynaptic density [GO:0014069],
membrane [GO:0016020],
sarcoplasmic reticulum [GO:0016529],
dendrite [GO:0030425],
perikaryon [GO:0043204],
spindle midzone [GO:0051233],
glutamatergic synapse [GO:0098978],