CAMK1

calcium/calmodulin dependent protein kinase I

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES

GO terms:

Biological Process:
protein phosphorylation [GO:0006468],
nucleocytoplasmic transport [GO:0006913],
cell cycle [GO:0007049],
signal transduction [GO:0007165],
positive regulation of neuron projection development [GO:0010976],
negative regulation of protein binding [GO:0032091],
regulation of protein localization [GO:0032880],
positive regulation of peptidyl-serine phosphorylation [GO:0033138],
regulation of protein binding [GO:0043393],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
positive regulation of protein export from nucleus [GO:0046827],
regulation of muscle cell differentiation [GO:0051147],
positive regulation of muscle cell differentiation [GO:0051149],
positive regulation of synapse structural plasticity [GO:0051835],
positive regulation of syncytium formation by plasma membrane fusion [GO:0060143],
positive regulation of dendritic spine development [GO:0060999],
positive regulation of protein serine/threonine kinase activity [GO:0071902],
positive regulation of protein acetylation [GO:1901985],
regulation of histone H3-K9 acetylation [GO:2000615],
multicellular organism development [GO:0007275],
nervous system development [GO:0007399],
metabolic process [GO:0008152],
phosphorylation [GO:0016310],
cell differentiation [GO:0030154],
regulation of synapse organization [GO:0050807],

Molecular Function:
calmodulin-dependent protein kinase activity [GO:0004683],
protein binding [GO:0005515],
calmodulin binding [GO:0005516],
ATP binding [GO:0005524],
nucleotide binding [GO:0000166],
catalytic activity [GO:0003824],
protein kinase activity [GO:0004672],
protein serine/threonine kinase activity [GO:0004674],
kinase activity [GO:0016301],
transferase activity [GO:0016740],

Cellular Component:
nucleus [GO:0005634],
cytoplasm [GO:0005737],
cytosol [GO:0005829],
postsynaptic density [GO:0014069],
glutamatergic synapse [GO:0098978],