CALCA

calcitonin related polypeptide alpha

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
20375903 Primary endothelial progenitor cells derived from blood Human, rat NO
20832068 Primary endothelial progenitor cells derived from cord blood Human NO
30352200 Heart Rat NO

GO terms:

Biological Process:
vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure [GO:0001984],
monocyte chemotaxis [GO:0002548],
inflammatory response [GO:0006954],
G-protein coupled receptor signaling pathway [GO:0007186],
adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189],
activation of adenylate cyclase activity [GO:0007190],
positive regulation of cytosolic calcium ion concentration [GO:0007204],
neuropeptide signaling pathway [GO:0007218],
embryo implantation [GO:0007566],
aging [GO:0007568],
feeding behavior [GO:0007631],
regulation of heart contraction [GO:0008016],
response to heat [GO:0009408],
regulation of receptor activity [GO:0010469],
negative regulation of ossification [GO:0030279],
activation of protein kinase activity [GO:0032147],
cellular protein metabolic process [GO:0044267],
negative regulation of bone resorption [GO:0045779],
negative regulation of transcription, DNA-templated [GO:0045892],
negative regulation of smooth muscle contraction [GO:0045986],
response to pain [GO:0048265],
detection of temperature stimulus involved in sensory perception of pain [GO:0050965],
regulation of cytosolic calcium ion concentration [GO:0051480],
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway [GO:0051482],
cellular response to tumor necrosis factor [GO:0071356],
cellular response to nerve growth factor stimulus [GO:1990090],
neurological system process involved in regulation of systemic arterial blood pressure [GO:0001976],
regulation of heart rate [GO:0002027],
cellular calcium ion homeostasis [GO:0006874],
neuromuscular junction development [GO:0007528],
regulation of blood pressure [GO:0008217],
negative regulation of neurological system process [GO:0031645],
vasodilation [GO:0042311],
negative regulation of blood pressure [GO:0045776],
positive regulation of ossification [GO:0045778],
positive regulation of cell adhesion [GO:0045785],
sperm capacitation [GO:0048240],

Molecular Function:
hormone activity [GO:0005179],
protein binding [GO:0005515],
calcitonin receptor binding [GO:0031716],
identical protein binding [GO:0042802],
receptor binding [GO:0005102],

Cellular Component:
extracellular region [GO:0005576],
extracellular space [GO:0005615],
nucleus [GO:0005634],
cytoplasm [GO:0005737],
neuronal cell body [GO:0043025],
terminal bouton [GO:0043195],
axon [GO:0030424],
neuron projection [GO:0043005],