CA2

carbonic anhydrase 2

Link to human ortholog


Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
30987592 MCF7 Breast Human YES

GO terms:

Biological Process:
kidney development [GO:0001822],
morphogenesis of an epithelium [GO:0002009],
response to pH [GO:0009268],
response to zinc ion [GO:0010043],
carbon dioxide transport [GO:0015670],
bicarbonate transport [GO:0015701],
positive regulation of synaptic transmission, GABAergic [GO:0032230],
positive regulation of cellular pH reduction [GO:0032849],
angiotensin-activated signaling pathway [GO:0038166],
odontogenesis of dentin-containing tooth [GO:0042475],
response to estrogen [GO:0043627],
regulation of anion transport [GO:0044070],
positive regulation of osteoclast differentiation [GO:0045672],
positive regulation of bone resorption [GO:0045780],
secretion [GO:0046903],
response to steroid hormone [GO:0048545],
regulation of intracellular pH [GO:0051453],
cellular response to fluid shear stress [GO:0071498],
positive regulation of dipeptide transmembrane transport [GO:2001150],
regulation of chloride transport [GO:2001225],

Molecular Function:
arylesterase activity [GO:0004064],
carbonate dehydratase activity [GO:0004089],
protein binding [GO:0005515],
zinc ion binding [GO:0008270],

Cellular Component:
cytoplasm [GO:0005737],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
microvillus [GO:0005902],
basolateral plasma membrane [GO:0016323],
axon [GO:0030424],
myelin sheath [GO:0043209],
apical part of cell [GO:0045177],
extracellular exosome [GO:0070062],