complement C8 gamma chain

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Li Fraumeni Human YES

GO terms:

Biological Process:
complement activation, alternative pathway [GO:0006957],
complement activation, classical pathway [GO:0006958],
cytolysis [GO:0019835],
regulation of complement activation [GO:0030449],
immune system process [GO:0002376],
innate immune response [GO:0045087],

Molecular Function:
retinol binding [GO:0019841],
complement binding [GO:0001848],
small molecule binding [GO:0036094],
macromolecular complex binding [GO:0044877],

Cellular Component:
extracellular region [GO:0005576],
membrane attack complex [GO:0005579],
extracellular exosome [GO:0070062],
blood microparticle [GO:0072562],
extracellular space [GO:0005615],