C2 calcium dependent domain containing 5

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES

GO terms:

Biological Process:
vesicle fusion [GO:0006906],
positive regulation of glucose transport [GO:0010828],
positive regulation of vesicle fusion [GO:0031340],
cellular response to insulin stimulus [GO:0032869],
insulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028],
positive regulation of glucose import [GO:0046326],
intracellular protein transmembrane transport [GO:0065002],
protein localization to plasma membrane [GO:0072659],
positive regulation of protein targeting to membrane [GO:0090314],
protein transport [GO:0015031],

Molecular Function:
calcium ion binding [GO:0005509],
calcium-dependent phospholipid binding [GO:0005544],
lipid binding [GO:0008289],

Cellular Component:
microtubule organizing center [GO:0005815],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
cell cortex [GO:0005938],
cytoplasmic vesicle membrane [GO:0030659],
ruffle membrane [GO:0032587],
cytoplasm [GO:0005737],
membrane [GO:0016020],
cytoplasmic vesicle [GO:0031410],
cell projection [GO:0042995],