complement C1s

Link to human ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
proteolysis [GO:0006508],
complement activation [GO:0006956],
complement activation, classical pathway [GO:0006958],
regulation of complement activation [GO:0030449],
innate immune response [GO:0045087],

Molecular Function:
serine-type endopeptidase activity [GO:0004252],
calcium ion binding [GO:0005509],
protein binding [GO:0005515],
identical protein binding [GO:0042802],

Cellular Component:
extracellular region [GO:0005576],
extracellular space [GO:0005615],
blood microparticle [GO:0072562],