C1RL

complement C1r subcomponent like

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Saos-2 Human YES

GO terms:

Biological Process:
complement activation, classical pathway [GO:0006958],
zymogen activation [GO:0031638],
innate immune response [GO:0045087],
immune system process [GO:0002376],

Molecular Function:
serine-type endopeptidase activity [GO:0004252],
peptidase activity [GO:0008233],
serine-type peptidase activity [GO:0008236],
hydrolase activity [GO:0016787],

Cellular Component:
extracellular space [GO:0005615],
extracellular exosome [GO:0070062],
extracellular region [GO:0005576],