BUB3

BUB3 mitotic checkpoint protein

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
23448364 MEF Lung Mouse NO

GO terms:

Biological Process:
mitotic sister chromatid segregation [GO:0000070],
ubiquitin-dependent protein catabolic process [GO:0006511],
mitotic spindle assembly checkpoint [GO:0007094],
attachment of spindle microtubules to kinetochore [GO:0008608],
anaphase-promoting complex-dependent catabolic process [GO:0031145],
protein localization to kinetochore [GO:0034501],
cell division [GO:0051301],
meiotic cell cycle [GO:0051321],
regulation of mitotic cell cycle phase transition [GO:1901990],
cell cycle [GO:0007049],
chromosome segregation [GO:0007059],
regulation of chromosome segregation [GO:0051983],

Molecular Function:
protein binding [GO:0005515],
ubiquitin binding [GO:0043130],

Cellular Component:
kinetochore [GO:0000776],
condensed chromosome kinetochore [GO:0000777],
nucleoplasm [GO:0005654],
cytosol [GO:0005829],
mitotic checkpoint complex [GO:0033597],
bub1-bub3 complex [GO:1990298],
chromosome, centromeric region [GO:0000775],
nucleus [GO:0005634],
chromosome [GO:0005694],