bone marrow stromal cell antigen 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Li Fraumeni Human YES
30987592 MCF7 Breast Human YES

GO terms:

Biological Process:
negative regulation of plasmacytoid dendritic cell cytokine production [GO:0002737],
humoral immune response [GO:0006959],
cell-cell signaling [GO:0007267],
multicellular organism development [GO:0007275],
cell proliferation [GO:0008283],
response to virus [GO:0009615],
negative regulation of endopeptidase activity [GO:0010951],
negative regulation of cell growth [GO:0030308],
negative regulation of cell migration [GO:0030336],
regulation of actin cytoskeleton organization [GO:0032956],
response to interferon-gamma [GO:0034341],
response to interferon-alpha [GO:0035455],
response to interferon-beta [GO:0035456],
B cell activation [GO:0042113],
positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123],
neutrophil degranulation [GO:0043312],
negative regulation of viral genome replication [GO:0045071],
innate immune response [GO:0045087],
defense response to virus [GO:0051607],
type I interferon signaling pathway [GO:0060337],
negative regulation of intracellular transport of viral material [GO:1901253],
immune system process [GO:0002376],

Molecular Function:
RNA binding [GO:0003723],
protein binding [GO:0005515],
metalloendopeptidase inhibitor activity [GO:0008191],
identical protein binding [GO:0042802],
protein homodimerization activity [GO:0042803],

Cellular Component:
cytoplasm [GO:0005737],
multivesicular body [GO:0005771],
Golgi apparatus [GO:0005794],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
integral component of plasma membrane [GO:0005887],
cell surface [GO:0009986],
membrane [GO:0016020],
apical plasma membrane [GO:0016324],
anchored component of membrane [GO:0031225],
azurophil granule membrane [GO:0035577],
membrane raft [GO:0045121],
extracellular exosome [GO:0070062],
endosome [GO:0005768],
integral component of membrane [GO:0016021],