BRMS1 transcriptional repressor and anoikis regulator

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES

GO terms:

Biological Process:
negative regulation of transcription from RNA polymerase II promoter [GO:0000122],
apoptotic process [GO:0006915],
histone deacetylation [GO:0016575],
negative regulation of NF-kappaB transcription factor activity [GO:0032088],
regulation of apoptotic process [GO:0042981],
negative regulation of transcription, DNA-templated [GO:0045892],
positive regulation of protein deacetylation [GO:0090312],
positive regulation of anoikis [GO:2000210],
cellular process [GO:0009987],

Molecular Function:
histone deacetylase activity [GO:0004407],
protein binding [GO:0005515],
histone deacetylase binding [GO:0042826],
NF-kappaB binding [GO:0051059],

Cellular Component:
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
Sin3-type complex [GO:0070822],