BRCA1 associated protein

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES

GO terms:

Biological Process:
MAPK cascade [GO:0000165],
Ras protein signal transduction [GO:0007265],
negative regulation of signal transduction [GO:0009968],
protein ubiquitination [GO:0016567],

Molecular Function:
nucleic acid binding [GO:0003676],
ubiquitin-protein transferase activity [GO:0004842],
protein binding [GO:0005515],
nuclear localization sequence binding [GO:0008139],
zinc ion binding [GO:0008270],
identical protein binding [GO:0042802],
ubiquitin protein ligase activity [GO:0061630],
transferase activity [GO:0016740],
metal ion binding [GO:0046872],

Cellular Component:
ubiquitin ligase complex [GO:0000151],
cytoplasm [GO:0005737],
cytosol [GO:0005829],
nuclear membrane [GO:0031965],