base methyltransferase of 25S rRNA 2 homolog

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA134 Skin, Lung Human YES

GO terms:

Biological Process:
methylation [GO:0032259],
cellular response to amino acid starvation [GO:0034198],
negative regulation of TORC1 signaling [GO:1904262],
rRNA methylation [GO:0031167],

Molecular Function:
methyltransferase activity [GO:0008168],
rRNA (adenine) methyltransferase activity [GO:0016433],
transferase activity [GO:0016740],
S-adenosyl-L-methionine binding [GO:1904047],

Cellular Component:
nucleolus [GO:0005730],
Iml1 complex [GO:1990130],