BMP6

bone morphogenetic protein 6

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2, Li-Fraumeni Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
negative regulation of transcription from RNA polymerase II promoter [GO:0000122],
skeletal system development [GO:0001501],
osteoblast differentiation [GO:0001649],
eye development [GO:0001654],
kidney development [GO:0001822],
positive regulation of endothelial cell proliferation [GO:0001938],
endochondral ossification [GO:0001958],
type B pancreatic cell development [GO:0003323],
cellular iron ion homeostasis [GO:0006879],
inflammatory response [GO:0006954],
immune response [GO:0006955],
positive regulation of cell proliferation [GO:0008284],
regulation of receptor activity [GO:0010469],
positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862],
response to activity [GO:0014823],
positive regulation of bone mineralization [GO:0030501],
BMP signaling pathway [GO:0030509],
male genitalia development [GO:0030539],
positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666],
response to magnesium ion [GO:0032026],
positive regulation of chondrocyte differentiation [GO:0032332],
positive regulation of aldosterone biosynthetic process [GO:0032349],
response to retinoic acid [GO:0032526],
regulation of apoptotic process [GO:0042981],
regulation of MAPK cascade [GO:0043408],
positive regulation of endothelial cell differentiation [GO:0045603],
positive regulation of neuron differentiation [GO:0045666],
positive regulation of osteoblast differentiation [GO:0045669],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
cell development [GO:0048468],
positive regulation of epithelial cell proliferation [GO:0050679],
positive regulation of protein secretion [GO:0050714],
cartilage development [GO:0051216],
response to glucocorticoid [GO:0051384],
positive regulation of SMAD protein import into nucleus [GO:0060391],
SMAD protein signal transduction [GO:0060395],
multicellular organismal iron ion homeostasis [GO:0060586],
cellular response to mechanical stimulus [GO:0071260],
cellular response to iron ion [GO:0071281],
cellular response to BMP stimulus [GO:0071773],
positive regulation of aldosterone secretion [GO:2000860],
ossification [GO:0001503],
multicellular organism development [GO:0007275],
cell differentiation [GO:0030154],
cellular response to extracellular stimulus [GO:0031668],

Molecular Function:
cytokine activity [GO:0005125],
transforming growth factor beta receptor binding [GO:0005160],
growth factor activity [GO:0008083],
protein heterodimerization activity [GO:0046982],
BMP receptor binding [GO:0070700],
protein binding [GO:0005515],

Cellular Component:
extracellular space [GO:0005615],
cytoplasm [GO:0005737],
vesicle [GO:0031982],
extracellular region [GO:0005576],