BIRC6

baculoviral IAP repeat containing 6

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
placenta development [GO:0001890],
ubiquitin-dependent protein catabolic process [GO:0006511],
apoptotic process [GO:0006915],
cell cycle [GO:0007049],
positive regulation of cell proliferation [GO:0008284],
negative regulation of peptidase activity [GO:0010466],
protein ubiquitination [GO:0016567],
regulation of cytokinesis [GO:0032465],
regulation of cell proliferation [GO:0042127],
negative regulation of apoptotic process [GO:0043066],
cell division [GO:0051301],
labyrinthine layer development [GO:0060711],
spongiotrophoblast layer development [GO:0060712],
negative regulation of extrinsic apoptotic signaling pathway [GO:2001237],
protein phosphorylation [GO:0006468],
negative regulation of endopeptidase activity [GO:0010951],

Molecular Function:
ubiquitin-protein transferase activity [GO:0004842],
cysteine-type endopeptidase inhibitor activity [GO:0004869],
protein binding [GO:0005515],
transferase activity [GO:0016740],
peptidase inhibitor activity [GO:0030414],
ubiquitin conjugating enzyme activity [GO:0061631],

Cellular Component:
spindle pole [GO:0000922],
nucleus [GO:0005634],
cytoplasm [GO:0005737],
endosome [GO:0005768],
Golgi apparatus [GO:0005794],
trans-Golgi network [GO:0005802],
microtubule organizing center [GO:0005815],
cytoskeleton [GO:0005856],
membrane [GO:0016020],
midbody [GO:0030496],
Flemming body [GO:0090543],