BICD2

BICD cargo adaptor 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA689 Skin, Lung Human YES

GO terms:

Biological Process:
retrograde vesicle-mediated transport, Golgi to ER [GO:0006890],
protein transport [GO:0015031],
protein localization to Golgi apparatus [GO:0034067],
mRNA transport [GO:0051028],
centrosome localization [GO:0051642],
regulation of microtubule cytoskeleton organization [GO:0070507],
minus-end-directed organelle transport along microtubule [GO:0072385],
microtubule anchoring at microtubule organizing center [GO:0072393],
microtubule-based movement [GO:0007018],

Molecular Function:
protein binding [GO:0005515],
cytoskeletal adaptor activity [GO:0008093],
Rab GTPase binding [GO:0017137],
dynactin binding [GO:0034452],
dynein light intermediate chain binding [GO:0051959],
dynein complex binding [GO:0070840],

Cellular Component:
nuclear envelope [GO:0005635],
annulate lamellae [GO:0005642],
nuclear pore [GO:0005643],
cytoplasm [GO:0005737],
Golgi apparatus [GO:0005794],
centrosome [GO:0005813],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
cytoplasmic vesicle [GO:0031410],
nucleus [GO:0005634],
cytoskeleton [GO:0005856],