BEST1

bestrophin 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Li Fraumeni Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
chloride transport [GO:0006821],
visual perception [GO:0007601],
transepithelial chloride transport [GO:0030321],
ion transmembrane transport [GO:0034220],
detection of light stimulus involved in visual perception [GO:0050908],
regulation of calcium ion transport [GO:0051924],
chloride transmembrane transport [GO:1902476],
ion transport [GO:0006811],

Molecular Function:
chloride channel activity [GO:0005254],
identical protein binding [GO:0042802],

Cellular Component:
cytosol [GO:0005829],
plasma membrane [GO:0005886],
membrane [GO:0016020],
integral component of membrane [GO:0016021],
basolateral plasma membrane [GO:0016323],
chloride channel complex [GO:0034707],