3-hydroxybutyrate dehydrogenase 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
fatty acid beta-oxidation [GO:0006635],
siderophore biosynthetic process [GO:0019290],
epithelial cell differentiation [GO:0030855],
heme metabolic process [GO:0042168],
ketone body biosynthetic process [GO:0046951],
iron ion homeostasis [GO:0055072],
oxidation-reduction process [GO:0055114],

Molecular Function:
3-hydroxybutyrate dehydrogenase activity [GO:0003858],
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [GO:0016628],
NAD binding [GO:0051287],
oxidoreductase activity [GO:0016491],

Cellular Component:
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],
cytosol [GO:0005829],
extracellular exosome [GO:0070062],